Can you take ashwagandha on an empty stomach? Ashwagandha does not have to be taken with food, but mild stomach upset is one of the side effects reported most often, so if your stomach is sensitive, taking it with food is a sensible first step. No human study we found compares taking it with and without food, and four of the five well-known trials we checked told people to take it after a meal. Here is what they said, how gummies fit in, and what to check if you take levothyroxine.
Key takeaways
- Food is not required. No human study we found has compared taking it with and without food.
- Most trials we checked said after a meal. Four of the five well-known trials we read told people to take their capsules after food or after a meal.
- A sensitive stomach is the real reason to eat first. Nausea and stomach upset are among the mild side effects reported most often in ashwagandha trials, in both the ashwagandha and placebo groups. Those trials used capsules, and none used our serving.
- Two gummies are not a meal. Taken before breakfast, ours are still taken on an empty stomach. Our product page suggests two gummies at breakfast, and says they can equally be taken in the evening.
- Taking levothyroxine? Speak to your GP first, as ashwagandha has been reported to affect thyroid hormone levels. Then ask your pharmacist about timing: our bottle contains 200mg of magnesium.
- Some people should not take it, or should check first. Our Ashwagandha Gummies are not for use in pregnancy or while breastfeeding, or by under-18s or anyone allergic to mushrooms (they contain lion's mane), ginkgo or any other ingredient. With a thyroid, liver, heart or autoimmune condition, high androgen levels, hormone-sensitive prostate cancer, epilepsy, a bleeding disorder, an operation coming up or another long-term condition, or on any regular medicine, including thyroid medication, sedatives and blood thinners, ask your GP or pharmacist first.
Can you take ashwagandha on an empty stomach?
Nothing in the research we read says you must take ashwagandha with food, and nothing says you must not. The question usually hides two others: will it upset my stomach, and will it still be absorbed? Some people do get mild stomach upset. On absorption, we could not find a study in people that has tested it.
What the ashwagandha trials said about food
Here is how five well-known ashwagandha root extract trials told people to take their capsules, from the methods section of each paper. None used a gummy.
| Trial (extract) | Who took part | What they were told |
|---|---|---|
| Chandrasekhar 2012 (KSM-66) | 64 adults under stress, 60 days | One capsule twice a day after food, with a glass of plain water |
| Salve 2019 (KSM-66) | 60 adults under stress, 8 weeks | One capsule twice a day after food, with milk or water |
| Langade 2019 (KSM-66) | 60 adults with insomnia, 10 weeks | One capsule twice a day with milk or water (food not mentioned) |
| Lopresti 2019 (Shoden) | 60 adults with mild stress, 60 days | One capsule once a day after dinner, with 250ml of water |
| Pakhale 2026 (KSM-66) | 1,002 adults with stress and anxiety, 8 weeks | One capsule after breakfast and one after dinner, with water |
When a paper said anything about food, it said after a meal. That was the routine the researchers chose, not something they tested: none compared it with an empty stomach.
Does ashwagandha absorb better with food?
Very few studies have measured withanolides, the compounds researchers focus on, in the blood at all: a 2024 review found four in humans. Two studies published in 2024 and 2025 gave ashwagandha extract to people who had fasted, and in the 2024 study the withanolides peaked in the blood roughly one to two hours after the dose. Neither compared fasting with eating, so they cannot tell you whether food changes the amount. The same gap applies to powders and drinks.
Stomach upset: the practical reason to eat first
The side effects recorded in ashwagandha trials are mostly mild. A 2026 systematic review of 23 trials in healthy adults listed nausea, indigestion and loose stools among the most common, alongside headache and drowsiness, in both the ashwagandha and the placebo groups.
The largest trial in that review followed 1,002 adults for eight weeks. Nausea was the most common side effect, reported by 2.0% of people taking ashwagandha and 3.2% taking a placebo. Everyone took their capsules after meals, so those figures say nothing about an empty stomach. None of the 23 trials used a gummy or our serving, so they cannot tell you how our bottle will suit you.
If your stomach is sensitive, or you feel queasy taking ashwagandha before eating, take it with food. If you feel fine either way, choose the time you will stick to. Our gummies also contain 200mg of magnesium, and more magnesium than you are used to can loosen stools. If stomach symptoms carry on, stop and speak to a pharmacist.
Do ashwagandha gummies count as food?
A capsule is swallowed with water. A gummy is chewed, and ours are made with fruit pectin, so you are eating a small piece of food. Two gummies are not a meal, though, so if you take them before breakfast, treat that as an empty stomach.
Our serving is two gummies a day, with 2,500mg of KSM-66 ashwagandha root extract, plus lion's mane, ginkgo biloba, 200mg of magnesium and vitamins B6 and B12. Our product page suggests two gummies at breakfast and says that, because the botanicals are not stimulants, they can equally be taken in the evening. Do not take more than two gummies in a day.
Ashwagandha on an empty stomach or with food: how to choose
- Sensitive stomach, or new to ashwagandha? Start with food, at a regular meal.
- Prefer it first thing? Before breakfast is an option if it agrees with you. The trials neither rule it out nor show it is better.
- Taking other supplements? Check the labels for ingredients that double up, especially magnesium.
- Pick a time you will remember. Take the same two gummies at the same point in your day.
Morning or night?
Four of the five trials above gave a capsule twice a day (one specified after breakfast and after dinner), and one gave a single capsule after dinner. None compared morning with evening, and we found no trial that tested a set gap before bed. If the evening suits you, having your gummies with or after your evening meal is easy to keep. If you take more than one of our bottles, see Morning, Midday, Evening: A Simple Way to Take Three Supplements.
Ashwagandha and levothyroxine: timing is the second question
If you take levothyroxine, you may wonder whether taking ashwagandha at night, away from your morning tablet, solves the timing. Two things come first.
Ashwagandha itself has been reported to affect thyroid hormone levels. The US National Center for Complementary and Integrative Health says it might interact with thyroid hormone medicines and does not recommend it for people with thyroid disorders. A 2026 review describes four published cases of an overactive thyroid in people taking ashwagandha, which settled after they stopped. So anyone with a thyroid condition or taking thyroid medication should speak to their GP before taking ashwagandha at all. Never stop or change a prescribed medicine without speaking to your doctor.
Levothyroxine has its own rules about food and supplements. The NHS advises taking it on an empty stomach, 30 to 60 minutes before your first meal of the day, any drink with caffeine such as tea or coffee, or any other medicine. It lists calcium and iron supplements, and antacids and other indigestion treatments, among things that may not mix well with it, and asks you to tell your doctor about any herbal remedies, vitamins or supplements.
That NHS page does not name magnesium or ashwagandha. Our Ashwagandha bottle contains 200mg of magnesium per two-gummy serving, and magnesium is a mineral, like the calcium and iron on that list. We cannot tell you how to time a prescribed medicine. If your GP is happy for you to take ashwagandha, take the bottle to your pharmacist and ask how far apart to take it from your levothyroxine.
Who should not take ashwagandha
Do not take our Ashwagandha Gummies if you:
- are pregnant, breastfeeding or under 18
- are allergic to mushrooms (lion's mane is a mushroom), to ginkgo or to any other ingredient
Ask your GP or pharmacist first if you:
- have a thyroid condition or take thyroid medication (for the ashwagandha)
- have a liver condition (for the ashwagandha)
- have a heart or autoimmune condition, high androgen levels or hormone-sensitive prostate cancer (for the ashwagandha)
- have epilepsy or take a medicine that can make seizures more likely, or have an operation coming up (for the ashwagandha and ginkgo)
- have a bleeding disorder, or take blood thinners such as warfarin, clopidogrel, dabigatran or aspirin, or anti-inflammatory painkillers such as ibuprofen (for the ginkgo)
- take efavirenz, an HIV medicine (for the ginkgo)
- take sedatives, sleep medication, or medicines for diabetes, blood pressure, seizures or the immune system (for the ashwagandha)
- take levodopa, isoniazid, phenytoin, theophylline or phenobarbital (for the vitamin B6)
- have another long-term condition, or take any other regular medicine
Whoever you are, if you notice yellowing of the skin or eyes, dark urine or persistent itching, stop and see your GP.
Looking at the Daily Three? None of its three bottles is for use in pregnancy or while breastfeeding. It adds our Saffron bottle. Our Saffron Gummies are not for use in pregnancy, while trying to get pregnant or breastfeeding, or by under-18s, anyone with phenylketonuria (PKU) or prone to allergies, or anyone allergic to any ingredient, and not with an autoimmune condition or immunosuppressants unless your doctor agrees. With bipolar disorder, a thyroid, liver, kidney or hormone-sensitive condition, high calcium, an operation coming up or another long-term condition, or on any regular medicine, including antidepressants, blood thinners, blood pressure medication and prescribed vitamin D, ask your GP or pharmacist first. Its third bottle is Sea Moss, and sea moss and bladderwrack are seaweeds that naturally carry iodine, in amounts that vary with species, harvest and season. The upper level for adults is 600 micrograms of iodine a day from all sources. If you have a thyroid condition or take thyroid medication, speak to your doctor first, and the same applies if you take lithium, amiodarone or any other iodine-containing medicine.
One more point that is specific to the UK. Ashwagandha is legal to sell as a food supplement here, but the Food Standards Agency asked for evidence on its safety in 2024 and has passed the responses to the Committee on Toxicity, the independent experts who advise it. The committee discussed a draft statement in September 2026 and, as of October 2026, no final view has been published. Elsewhere in Europe, where the concerns centre on rare liver and thyroid reports, Denmark has banned ashwagandha in supplements, France advises some groups to avoid it and the Netherlands has proposed tighter rules. We will update this page when the UK position is published.
Food supplements are not a substitute for a varied diet and a healthy lifestyle.
Also taking our Saffron bottle? Add up the magnesium
There is 200mg of magnesium in our Ashwagandha bottle and 100mg in our Saffron bottle, so 300mg a day if you take both. Three published figures put that in context:
- The EU Nutrient Reference Value is 375mg a day, from all sources. 300mg is 80% of that.
- The UK Expert Group on Vitamins and Minerals set a guidance level of 400mg a day for supplemental magnesium. 300mg is below it.
- The EU Scientific Committee on Food set an upper level of 250mg a day for magnesium from supplements. 300mg is above it.
The usual consequence of taking more supplemental magnesium than you are used to is loose stools, and it tends to settle. If that happens, or if you already take a magnesium supplement, take the two bottles on alternate days or drop one. Sea Moss has no added vitamins or minerals, so the Daily Three does not change the total.
KSM-66 + Lion's Mane + Ginkgo
Ashwagandha Gummies
£16.99 for 60 Mixed Berries gummies, a 30-day supply. 2,500mg KSM-66 ashwagandha root extract per two-gummy serving. Free UK delivery.
Want all three bottles? The Daily Three is £31.99, 35% off the £49.97 for Sea Moss, Ashwagandha and Saffron bought separately.
The Daily Three adds two more bottles, each with its own cautions. Sea moss and bladderwrack are seaweeds and carry iodine, and the Saffron bottle contains saffron and rhodiola, so if you have a thyroid condition or take antidepressants, read the safety section before you choose the Daily Three.
List prices, before any discount code, correct on 27 October 2026.
Frequently asked questions
Can you take ashwagandha on an empty stomach?
Ashwagandha does not have to be taken with food, and we found no human study comparing it with and without food. Mild stomach symptoms such as nausea are among the side effects reported most often, so if your stomach is sensitive, taking it with food is a sensible first step. Our Ashwagandha Gummies are not for use in pregnancy or while breastfeeding, or by under-18s or anyone allergic to mushrooms (they contain lion's mane), ginkgo or any other ingredient. With a thyroid, liver, heart or autoimmune condition, high androgen levels, hormone-sensitive prostate cancer, epilepsy, a bleeding disorder, an operation coming up or another long-term condition, or on any regular medicine, including thyroid medication, sedatives and blood thinners, ask your GP or pharmacist first.
Should ashwagandha be taken with food?
It does not have to be. We found no human study testing whether food changes how much ashwagandha is absorbed. Taking it with a meal is still sensible if your stomach is sensitive, and it matches how four of the five well-known trials we checked were run.
When should you take ashwagandha, before or after a meal?
After a meal is the pattern four of the five well-known ashwagandha trials we checked used, and the easier choice if an empty stomach feels unsettled. No trial we found compared before with after, so the research does not favour either. Our product page suggests taking our Ashwagandha Gummies at breakfast.
Can you take ashwagandha at night?
Evening is an option. Our product page says the botanicals in our Ashwagandha Gummies are not stimulants, so they can equally be taken in the evening. No trial we found compared morning with night, so choose the time you will remember every day.
How long before bed should you take ashwagandha?
We found no trial that tested a set gap before bed. The ashwagandha trials we read that named an evening time said after dinner, not at bedtime. If you take ashwagandha gummies in the evening, with or after your evening meal is a simple routine.
Can I take ashwagandha at night if I take levothyroxine?
Speak to your GP before taking ashwagandha at all, because it has been reported to affect thyroid hormone levels. If your GP agrees, ask your pharmacist when to take it. The NHS advises taking levothyroxine on an empty stomach, 30 to 60 minutes before your first meal, caffeine or any other medicine, and lists calcium and iron supplements and indigestion remedies among things that may not mix well with it. Our Ashwagandha Gummies contain 200mg of magnesium per serving, so show your pharmacist the label.
References
- Chandrasekhar K, Kapoor J, Anishetty S. "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults." Indian J Psychol Med, 2012;34(3):255-262. doi:10.4103/0253-7176.106022
- Salve J et al. "Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study." Cureus, 2019;11(12):e6466. doi:10.7759/cureus.6466
- Langade D et al. "Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study." Cureus, 2019;11(9):e5797. doi:10.7759/cureus.5797
- Lopresti AL et al. "An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study." Medicine (Baltimore), 2019;98(37):e17186. doi:10.1097/MD.0000000000017186
- Pakhale K et al. "Safety of 8-Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi-Center, Double-Blinded, Placebo-Controlled Study." Phytother Res, 2026;40(8):5005-5015. doi:10.1002/ptr.70315
- Coope OC et al. "Back to the Roots: Safety and Tolerability of Standardised Ashwagandha (Withania somnifera) Root Extract in Healthy Adults-A Systematic Review of Biomarkers and Adverse Events." Pharmaceuticals (Basel), 2026;19(5):725. doi:10.3390/ph19050725
- Speers AB, Lozano-Ortiz A, Soumyanath A. "Quantifying Withanolides in Plasma: Pharmacokinetic Studies and Analytical Methods." Nutrients, 2024;16(22):3836. doi:10.3390/nu16223836
- Vaidya VG et al. "Clinical pharmacokinetic evaluation of Withania somnifera (L.) Dunal root extract in healthy human volunteers: A non-randomized, single dose study utilizing UHPLC-MS/MS analysis." J Ethnopharmacol, 2024;322:117603. doi:10.1016/j.jep.2023.117603
- Rathi P, Kim SK. "Randomized, Double-Blind, Crossover Study Comparing the Bioavailability of 4 Ashwagandha (Withania somnifera (L.) Dunal) Extracts in Healthy Adults Under Fasting Condition." Curr Ther Res Clin Exp, 2025;103:100805. doi:10.1016/j.curtheres.2025.100805
- National Center for Complementary and Integrative Health. "Ashwagandha: Usefulness and Safety." Last updated March 2023. nccih.nih.gov.
- Winther K. "The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A Review." Nutrients, 2026;18(5):871. doi:10.3390/nu18050871
- NHS. "Levothyroxine: a medicine for an underactive thyroid (hypothyroidism)." Page last reviewed 6 July 2026. nhs.uk.
- European Medicines Agency, HMPC. "EU herbal monograph on Ginkgo biloba L., folium." EMA/HMPC/321097/2012.
- Björnsson HK et al. "Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network." Liver Int, 2020;40(4):825-829. doi:10.1111/liv.14393
- Brendler T et al. "Ashwagandha: Is It Safe? Part 1: A Regulatory Review." Phytother Res, 2026;40(8):4845-4857. doi:10.1002/ptr.70151
- Food Standards Agency. "Summary of responses to call for evidence on Ashwagandha." 25 June 2026. gov.uk.
- Committee on Toxicity. Meeting of 8 September 2026, item TOX/2026/30, third draft statement on ashwagandha. gov.uk.
- European Commission. Regulation (EU) No 1169/2011, Annex XIII: Nutrient Reference Values.
- Expert Group on Vitamins and Minerals. "Safe Upper Levels for Vitamins and Minerals." Food Standards Agency, 2003.
- Scientific Committee on Food. "Opinion on the Tolerable Upper Intake Level of Magnesium." European Commission, 2001.
Food supplements are not intended to treat, cure or prevent any disease. If you are pregnant, breastfeeding, taking medication, or have a medical condition, consult a healthcare professional before use.